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Ideal Body Weight
P/F Ratio
ROX Index
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Ideal Body Weight
P/F Ratio
ROX Index
Driving Pressure
Airway Resistance
Static Compliance
Minute Ventilation
Desired FiO₂
Winter’s Formula
Desired RR
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Data Management
About
Version:
1.0.0
Developer:
Yousef Sayed
- For ventilator settings: IBW is used instead of actual body weight when setting tidal volume in order to prevent volutrauma, especially in obese patients
- In nutritional planning: Used to calculate protein and caloric requirements more accurately
- In medication dosing: Certain drugs are dosed based on IBW to avoid overdosing in obese patients
Men: IBW = 50 kg + 2.3 × (height in inches − 60)
Women: IBW = 45.5 kg + 2.3 × (height in inches − 60)
Women: IBW = 45.5 kg + 2.3 × (height in inches − 60)
Clinical Pearl: Ventilator tidal volumes should always be based on IBW, not actual weight, to prevent alveolar overdistention and volutrauma.
- Prevents complications in mechanical ventilation by standardizing tidal volume
- Ensures more reliable estimates of metabolic and drug dosing needs
- Provides a fair comparison across patients regardless of obesity or underweight status
Input Parameters
Results
Ideal Body Weight:
-
Target Tidal Volume (Vt):
Healthy Lung (6-8 ml/kg):
-
ARDS (4-6 ml/kg):
-
COPD (8-10 ml/kg):
-
Spinal Cord Injury (10-15 ml/kg):
-
- To assess severity of hypoxemia in ICU patients, especially suspected ARDS
- For monitoring oxygenation response to therapy (e.g., prone positioning, recruitment maneuvers)
- To track oxygenation trends during progression or recovery of lung injury
P/F Ratio = PaO2 ÷ FiO2
Clinical Pearl: The P/F ratio is a cornerstone in ARDS diagnosis; declining values signal worsening shunt and oxygenation failure.
- Provides an objective marker for ARDS diagnosis and severity stratification
- Helps clinicians decide when to escalate support (higher PEEP, proning, ECMO referral)
- Allows comparison of oxygenation efficiency independent of FiO₂ level
Input Parameters
Results
P/F Ratio:
-
Interpretation:
P/F ratio interpretation will appear here.
- In patients receiving high-flow nasal cannula (HFNC) for hypoxemic respiratory failure
- To guide decision-making about whether HFNC is effective or if intubation is likely needed
- During monitoring after HFNC initiation (2, 6, and 12 hours)
ROX Index = (SpO2 ÷ FiO2) ÷ Respiratory Rate
Clinical Pearl: A ROX ≥4.88 predicts HFNC success; persistently low values identify patients at high risk of HFNC failure and need for intubation.
- Provides an early warning tool to avoid delayed intubation, which increases mortality
- Combines oxygenation and work of breathing in a single simple number
- Helps RTs and physicians standardize evaluation of HFNC patients
Input Parameters
Results
ROX Index:
-
Interpretation:
ROX index interpretation will appear here.
- In all ventilated patients, especially ARDS, as part of lung-protective ventilation strategies
- To assess adequacy of tidal volume relative to lung compliance
- During adjustments of PEEP and VT to ensure pressures remain safe
ΔP = Pplat − PEEP
Clinical Pearl: Driving pressure correlates more strongly with survival in ARDS than tidal volume or plateau pressure—keep it <15 cmH₂O.
- Strong predictor of survival in ARDS compared to VT or Pplat alone
- Guides ventilator adjustments to minimize alveolar overdistention
- Provides individualized lung-protective targets based on compliance
Input Parameters
Results
Driving Pressure (ΔP):
-
Interpretation:
Driving pressure interpretation will appear here.
- In mechanically ventilated patients to detect increased resistance (bronchospasm, secretions, tube obstruction)
- To evaluate effectiveness of bronchodilator therapy
- When unexplained high peak pressures are present
Raw = (Ppeak − Pplat) ÷ Flow (L/s)
Clinical Pearl: An elevated difference between peak and plateau pressures highlights increased airway resistance from obstruction or bronchospasm.
- Helps differentiate between airway resistance vs lung compliance problems
- Guides treatment such as suctioning, bronchodilators, or checking tube patency
- Provides quantitative monitoring for airway disease progression
Input Parameters
Results
Airway Resistance:
-
Interpretation:
Airway resistance interpretation will appear here.
- In intubated patients to assess stiffness of lungs and chest wall
- To monitor progression of ARDS, pulmonary edema, or restrictive disease
- When evaluating response to therapy (PEEP changes, recruitment)
Cstat = VT ÷ (Pplat − PEEP)
Clinical Pearl: Progressive decline in compliance reflects worsening lung stiffness; very low values (<20 mL/cmH₂O) are poor prognostic indicators.
- Differentiates between stiff vs compliant lungs, crucial for ventilation strategies
- Helps in optimizing PEEP and VT to prevent volutrauma/barotrauma
- Provides a trend marker for monitoring lung condition over time
Input Parameters
Results
Static Compliance:
-
Interpretation:
Static compliance interpretation will appear here.
- To evaluate overall adequacy of ventilation (CO₂ removal)
- In mechanically ventilated patients, to ensure set RR and VT provide enough ventilation
- To detect increased demand (fever, metabolic acidosis, sepsis)
VE = VT × RR
Clinical Pearl: Elevated VE may indicate compensatory response to metabolic acidosis or rising ventilatory workload before overt decompensation.
- Ensures patient's ventilatory needs are being met
- Helps identify conditions with excessive ventilatory demand requiring support
- Central to predicting and adjusting PaCO₂
Input Parameters
Results
Target Minute Ventilation:
-
Interpretation:
Minute ventilation interpretation will appear here.
- When titrating oxygen therapy to maintain safe PaO₂ or SpO₂ targets
- To calculate the FiO₂ needed after ABG results show hypoxemia
- During weaning or escalation of oxygen support
Desired FiO2 = (PaO2 desired × FiO2 known) ÷ PaO2 known
Clinical Pearl: Target the lowest FiO₂ that maintains adequate oxygenation; prolonged high FiO₂ predisposes to oxygen toxicity and absorption atelectasis.
- Provides a rational approach for FiO₂ adjustments instead of guesswork
- Helps balance adequate oxygenation with prevention of oxygen toxicity
- Optimizes O₂ delivery in both acute and chronic care
Input Parameters
Results
Desired FiO₂:
-
Interpretation:
Desired FiO₂ interpretation will appear here.
- In metabolic acidosis (low HCO₃⁻) to check if respiratory compensation is appropriate
- During ABG interpretation to rule out mixed disorders
- Particularly important in diabetic ketoacidosis, renal failure, lactic acidosis
Expected PaCO2 = (1.5 × HCO3-) + 8 ± 2
Clinical Pearl: Deviation of actual PaCO₂ from the expected range indicates the presence of a mixed acid–base disorder.
- Differentiates simple vs mixed acid-base disorders
- Prevents missing a secondary respiratory problem
- Guides safe ventilator management in metabolic acidosis
Input Parameters
Results
Expected PaCO₂:
-
Expected Range (±2):
-
Interpretation:
interpretation will appear here
- When PaCO₂ is not at target and ventilator rate needs adjustment
- To correct hypercapnia or hypocapnia safely
- During weaning trials or controlled ventilation adjustments
Desired RR = (Current RR × Current PaCO2) ÷ Desired PaCO2
Clinical Pearl: When adjusting RR for PaCO₂ correction, always assess for risk of auto-PEEP and ensure adequate exhalation time.
- Provides a precise, safe way to adjust ventilator RR to reach target PaCO₂
- Reduces trial-and-error in ventilator changes
- Prevents complications of overventilation (alkalosis) or underventilation (acidosis)
Input Parameters
Results
Required RR:
-
Interpretation:
Result guidance will appear here.